Two young women come up short on the funds needed to live in New York City. Lauren Powell (Lauren Miller), a reserved overachiever, is suddenly on her own after boyfriend Charlie (James Wolk) abruptly breaks up with her. Katie Steele (Ari Graynor), an irrepressible free spirit, is about to forfeit a dream residence unless she finds an apartment-mate. Their mutual best friend Jesse (Justin Long) has the bright idea that they room together, even though he well knows that they are polar opposites who haven’t spoken since they met in college and then fell out within minutes. When Lauren and Katie meet up anew at Jesse’s behest, they’re still an at-odds couple…but, without options, Lauren reluctantly moves in. With nothing in common, she and Katie barely speak – until Lauren discovers that Katie is working as a phone-sex operator. This is, Lauren reasons, a good business opportunity; together, they will buy a land line and start up their own answering service. Katie is – it would seem – already in her element, and Lauren catches on quick; it’s not long before the blushing subsides and the candid chatting becomes second nature to her. It’s a long, hot summer for the newly minted team and their callers; Lauren puts her job hunt on hold while Katie considers the courtship ministrations of caller Sean (Mark Webber). But as their business partnership takes off, Lauren and Katie’s newfound friendship finds unexpected challenges that may leave them both, as they say, hanging on the telephone.