“Duets” is a road-trip film about six individuals who throw off the binds of their pre-determined lives and strive to fulfill their dreams. The metaphor for this is Karaoke _ the courage to stand up, sing and be free. They are: a waitress (BELLO) from Wheeling, West Virginia desperate to get to California to become a recording star, an ex-con (BRAUGHER) unwilling to bend to the rules of society who sings with the voice of an angel, a salesman (GIAMATTI) who melts down while chasing the American Dream, a seasoned Karaoke hustler (LEWIS) who is disconnected from everybody and everything, an innocent Vegas showgirl (PALTROW) searching for family and love, and a young down-on-his-luck cab driver (SPEEDMAN). Each is searching for the meaning of life.