Two renegade fallen angels attempt to jerry-rig the entire cosmological system — unless a rag-tag group of humans can stop them. Loki (Matt Damon) and Bartleby (Ben Affleck) are searching for a way out of everlasting exile in Wisconsin when they stumble upon the perfect return-to-paradise plan: a loophole in church dogma that will allow them to re-enter Heaven if they pass under the blessed arch of a New Jersey cathedral. There’s only one minor drawback: should they succeed, they’ll also obliterate all human existence.

So it is that the fate of the world comes to rest upon a woman who just happens to be having a crisis of faith. Bethany (Linda Fiorentino), the heroine, is a woman who feels her prayers haven’t been answered when, out of nowhere, a heralding angel appears in her bedroom and declares her the potential savior of humanity. This abrupt meeting sets her off on an extraordinary journey of mystery, comedy and suspense as she is transported to a fantastical world of celestial characters and spirited adventure. Along the way she will meet up with a heaven-sent messenger (Alan Rickman), an apostle with a 2,000 year old beef (Chris Rock), a hotheaded demon (Jason Lee), a heavenly Muse (Salma Hayek) and two unlikely Prophets known as Jay and Silent Bob as they each discover the power of their own individual faith.