From director Martin Scorsese, and based on the best-selling thriller by Dennis Lehane, comes Shutter Island, a tale of haunting mystery and psychological suspense that unfolds entirely on a fortress-like island housing a hospital for the criminally insane.

The year is 1954, at the height of the Cold War, when U.S. Marshal Teddy Daniels (DiCaprio) and his new partner Chuck Aule (Ruffalo) are summoned to Shutter Island to investigate the implausible disappearance of a brilliant multiple murderess from a locked room within the impenetrable Ashecliffe Hospital. Surrounded by probing psychiatrists and dangerously psychopathic patients on the remote, windswept isle, they arrive into an eerie, volatile atmosphere that suggests nothing is quite what it seems.

With a hurricane bearing down on them, the investigation moves rapidly. Yet, as it mounts, the mysteries multiply. There are hints and rumors of dark conspiracies, sordid experimentation, repressive mind control and secret wards, but elusive proof. Moving in the shadows of a hospital haunted by the terrible deeds of its slippery inhabitants and the unknown agendas of its equally ingenious doctors, Teddy begins to realize that the deeper he pursues the investigation, the more he will be forced to confront some profound and devastating fears.