Alex Whitman (Matthew Perry) is a straight-laced corporate type from Manhattan. Isabel Fuentes (Salma Hayek) is a fiery Mexican-American who believes in the power of destiny. Neither gave a thought to where a single night of passion would lead, but the whims of chance had other ideas. When they meet three months late, she’s pregnant and they decide to get married. It’s a long way from Manhattan to Las Vegas, but Alex is beginning to think it was worth the trip. Fools Rush In tells the funny, romantic story of fated lovers trying their luck at the world’s oldest game: love.